MORPHOLOGICAL CHANGES IN THE GASTRIC MUCOSA IN CHRONIC KIDNEY DISEASE IN CHILDREN
Keywords:
children, chronic kidney disease, glucocorticosteroids, stomachAbstract
This article discusses changes in the mucous membranes of the stomach and duodenum observed by esophagogastroduodenoscopy in children aged 7–17 years with chronic kidney disease that were treated with glucocorticosteroids for six months or longer. As a result of the analysis, chronic gastroduodenitis was detected in 65 (55.1%) cases and gastrobioptates were obtained. Morphological alterations in the cellular composition of the gastric mucosal glands were analyzed in relation to the severity of gastric mucosa inflammation, with morphometric evaluation of the cellular composition conducted to characterize these alterations. Morphometric analysis of the samples taken from 26 healthy children was performed to define reference values to characterize the cellular composition of the gastric mucosal glands as myometria measures
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